Granulomatous mastitis with erythema nodosum: A case report and mini-review of the literature

Granulomatous mastitis (GM) is a rare chronic inflammatory disease of the breast, often mistaken for malignancy. The present study describes the case of a patient with GM associated with erythema nodosum (EN). A 37-year-old female patient presented with a 2-month history of a painful mass in the left breast, accompanied by bilateral skin lesions on the lower limbs.

A physical examination revealed a tender breast mass (3 cm in size) and multiple erythematous subcutaneous nodules on the lower limbs. Laboratory tests revealed an elevated white blood cell count and hypochromic microcytic anemia. A breast ultrasonography demonstrated a hypoechoic mass in the left breast.

Core needle biopsy revealed non-caseating granulomas consistent with GM. The final diagnosis was GM associated with EN. Treatment with prednisolone and colchicine led to the resolution of symptoms within 4 weeks.

In addition, a brief …