Hyperfunctioning Papillary Thyroid Carcinoma

A 40-year-old male presented with symptoms of palpitations, excessive sweating, and weight loss for a one-month duration. The patient reported no significant past medical history, surgical history, or family history.

HISTOPATHOLOGY

1/1/20161 min read

Patient Information:
A 40-year-old male presented with symptoms of palpitations, excessive sweating, and weight loss for a one-month duration. The patient reported no significant past medical history, surgical history, or family history.

Clinical Findings:
Upon examination, the patient showed symptoms consistent with hyperthyroidism but did not display any visible thyroid mass or notable cervical lymphadenopathy.

Diagnostic Assessment:
Laboratory results showed elevated serum thyroid hormone levels, indicating hyperthyroidism. Ultrasound of the neck revealed multinodular goiter with several hypoechoic nodules within the thyroid, most notably a hyperfunctioning nodule. A fine needle aspiration (FNA) biopsy of the nodule confirmed the presence of papillary thyroid carcinoma.

Therapeutic Intervention:
The patient underwent a total thyroidectomy followed by central neck dissection to remove affected lymph nodes. The histopathological examination revealed hyperfunctioning papillary thyroid carcinoma with minimal vascular invasion and no evidence of distant metastasis.

Follow-up:
Post-operative recovery was uneventful, and the patient was started on levothyroxine therapy for thyroid hormone replacement. He was scheduled for regular follow-up with serial neck ultrasound and serum thyroglobulin levels to monitor for recurrence.

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