Warthin-like subtype of papillary thyroid carcinoma

Warthin-like papillary thyroid carcinoma (WL-PTC) is a rare subtype of papillary thyroid carcinoma (PTC), defined by oncocytic cells with typical papillary thyroid cancer nuclear features and dense lymphocytic infiltration. Despite its rarity, it usually has a favorable prognosis. A retrospective case series of six patients diagnosed between January 2020 and November 2024 was reviewed, including clinical, imaging, cytology, surgical, histopathological, and follow-up data.

The group consisted of five females and one male, with the ages of patients ranging from 23 to 54 years. Patients presented with neck nodules, localized pain, or systemic symptoms. All underwent total thyroidectomy, and four also had lymph node dissections, with two cases showing nodal metastasis.

Histopathological examination confirmed WL-PTC, either alone or alongside conventional PTC. No recurrence or residual disease was detected …