Epithelial-Myoepithelial Carcinoma of Salivary Glands: A Tertiary Center Experience

MethodsThis study was conducted between February 2020 and December 2025. Patients with a histopathologically confirmed diagnosis of epithelial-myoepithelial carcinoma were identified. Complete medical records containing demographics, clinical presentation, imaging results, histological features, treatment approaches, and follow-up results were included in the cases.ResultsFive patients were identified, of which 4 (80%) were females.

The mean age was 56±9.38 years. Two patients (40%) presented with painless post-auricular swelling, 1 (20%) with submandibular swelling, and 2 (40%) were incidental findings. Histopathological examination confirmed EMC in all cases.

Free margins were achieved in 3 tumors (60%). No recurrence was observed during a mean follow-up of 24±28.92 months.ConclusionEpithelial-myoepithelial carcinoma is a very rare tumor. It requires histopathological evaluation for accurate diagnosis, and complete surgical excision offers favorable short-term outcomes.

Further studies are needed to better define its clinical characteristics and outcomes.