Hodgkin lymphoma of the parotid gland: A case report with literature review

Classical Hodgkin lymphoma (HL) involving the parotid gland is an exceedingly rare form of extra-nodal lymphoma. This study presents a case of classical HL manifesting as a parotid mass. A 72-year-old male presented with a painless right parotid mass, night sweats, and weight loss.

Initial evaluation suggested a malignant parotid mass with associated lymphadenopathy; however, fine needle aspiration yielded inconclusive results. Surgical excision confirmed classical HL through histopathology and immunohistochemistry. A review of HL and non-Hodgkin lymphoma in the parotid gland, including cases across a patient age range of 14 to 80 years, revealed that most patients presented with non-tender parotid swelling.

Imaging demonstrated diverse features, including round masses and cystic lesions. Needle biopsies often yielded inconclusive results, with diagnosis confirmed after surgery. Treatment …