Granulomatous mastitis co-existing with breast cancer: A case report and mini-review of the literature

Granulomatous mastitis (GM) is a rare inflammation of the breast marked by non-caseating granulomatous lesions near the breast ducts and lobules. Reports of GM coinciding with breast cancer are rare. The present study describes the case of a patient with GM, high-grade high-grade ductal carcinoma in situ (DCIS), and invasive ductal carcinoma were present in the same breast.

A 36-year-old woman with a 2-week history of left breast pain was found to have a large, firm lump. A core needle biopsy led to the diagnosis of DCIS and suppurative GM. The patient was initially treated with analgesics and antibiotics for 20 days.

Eventually, the patient underwent a complete mastectomy with immediate reconstruction using a TRAM flap. A subsequent histopathological examination revealed invasive ductal carcinoma of no specific type, poorly differentiated, with extensive DCIS and suppurative GM. Upon the last follow …